In the SUSTAIN-6 trial, injectable semaglutide demonstrated a notable effect in reducing the incidence of nonfatal stroke (hazard ratio [HR] 0.61
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An injection is given once weekly Rybelsus- tablet given once daily Exenatide: It is sold as Byetta is injected twice daily Bydureon injected once a week Liraglutide: the available brands are Victoza is used to treat Type 2 DM Saxenda used to manage chronic weight management Dulaglutide: It is marketed as Trulicity
Nausea/vomiting, constipation/bloating or diarrhea is one of the most common side effects and unless it is transient, can make the medications intolerable for some
However, the risk of developing thyroid cancer was 1.85 times higher within the first year after initiating GLP-1 RA treatment compared with the other three drugs
It is important to clarify that these capsules do not contain pharmaceutical GLP-1 receptor agonists like Semaglutide