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In LEADER, the use of liraglutide was associated with a 0.4% HbA1c reduction compared with the placebo (Zinman et al., 2018)

After 18 months of treatment, the patient's cognitive function test scores improved from 2/12 in the average category at baseline to 7/12 in the average category, demonstrating substantial cognitive enhancement

Floridians may recognize the following brand names of GLP-1 weight loss drugs: Ozempic (semaglutide from Novo Nordisk) Rybelsus (semaglutide from Novo Nordisk) Wegovy (semaglutide from Novo Nordisk) Mounjaro (tirzepatide from Eli Lilly and Company) Zepbound (tirzepatide from Eli Lilly and Company) Saxenda (liraglutide from Novo Nordisk) Victoza (liraglutide from Novo Nordisk) Trulicity (dulaglutide from Eli Lilly and Company) Bursor & Fisher, P.A

If you are planning long-term tirzepatide use, reconstitute at 20 mg/mL to keep all doses under 1 mL

Key players include Novo Nordisk, Eli Lilly, Sanofi, Boehringer Ingelheim, AstraZeneca, Amgen, Merck & Co., and Bristol-Myers Squibb

Regular LFTs are crucial to detect and address any liver problems early, ensuring ongoing liver health during treatment