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Calreticulin as a hydrophilic chimeric molecular adjuvant enhances Igg responses to the spike protein of severe acute respiratory syndrome coronavirus

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[6] The concern with any unregulated IGF-1R agonist is precisely that it could stimulate the survival and proliferation of pre-neoplastic or neoplastic cells, which is why IGF-1R has been an oncology drug target for inhibition rather than activation

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