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Though this energy (on moderate binding affinity) amounts to around only 30 kJ mol -1 , i.e., that of just a few hydrogen bonds, if it were retained by the enzyme and not dissipated, it would still be enough to denature the protein (the slightly greater stability of catalases mentioned earlier, not withstanding)

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Keshelava N, Frgala T, Krejsa J, Kalous O, Reynolds CP

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