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To be transported across the mitochondrial membrane, LCFAs are activated in the cytoplasm by conversion to long-chain fatty acyl-CoAs (LCFA-CoAs)

This happens because of the buildup of uric acid crystals

8 Conclusion The investigation of metformin as an antioxidant intervention has yielded promising outcomes in various studies both in vitro and in vivo

However, the limited availability of clinical data makes it challenging to draw evidence-based conclusions about the potential adverse effects of finasteride

10.1210/jc.2006-0110 22

Falk, D