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10.1186/s10194-018-0956-x J

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These additionally internalized receptors are for the most part dimerized with MC3R (Schellekens et al., 2013), suggesting that dimerization with MC3R may not only lead to reduced efficiency of GHSR1a signaling, but also to reduced surface expression of the receptor

Yang XR, Qiu YT, Zhao YQ, Chi CF, Wang B

Surgical removal of these TDLNs abolished PD-1/PD-L1 checkpoint blockade-induced tumor regression and was associated with decreased immune infiltration in the primary tumors (34)

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