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Effect of -lipoic acid on symptoms and quality of life in patients with painful diabetic neuropathy

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Muresanu, MD, PhD Department of Neurosciences and RoNeuro Institute Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania Professor Dafin Muresanu has been a principal investigator for multiple large-scale Cerebrolysin clinical trials since the early 2000s, leading landmark studies that have shaped understanding of this peptide preparations potential in stroke and traumatic brain injury

Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction

tuberculosis infection, as well as decreased levels of proinflammatory cytokines IL-1, TNF-, and IL-6, and increased levels of IFN-, promoting the host immune response to contain infection successfully