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Homocysteine, through activation of NMDA receptors, induces Ca +2 , leading to excitotoxicity, astrocyte activation with release inflammatory mediators, and matrix metalloproteinase (MMP) activation with subsequent BBB injury and microvascular inflammation (Kamat et al

People living with T2DM have an increased risk of developing complications, including chronic kidney disease (CKD), which itself is associated with increased mortality

The transaction is pending regulatory approval and is expected to close by the end of 2024.