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This work will focus on 2D cell culture models (endothelial cell lines and primary ECs), 3D cell culture systems (scaffold-free and scaffold-based), and 3D cell culture models (such as organ-on-a-chip)

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Systematic review of randomized controlled trials on interventions for melasma: An abridged Cochrane review

While each offers impressive benefits on its own, their combined effects create a synergistic approach to achieving radiant, youthful skin that goes far beyond what either compound can accomplish alone