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Thanabhorn S, Jaijoy K, Thamaree S, Ingkaninan K, Panthong A

The results were dramatic

in patients with type 2 diabetes mellitus, the incretin effect is responsible for less than 20% of the insulin response to an oral glucose load, whereas it accounts for roughly two-thirds of the response

GLP-1s and Menopause Weight Gain: Why Hormone Replacement Therapy (HRT) Improves Weight Loss Results If you're a woman in her 40s or 50s struggling with weight that won't budge no matter what you do, you're not imagining things

GLP1 also decreases both the release and breakdown of stored carbohydrates as well as the synthesis of new glucose by inhibiting the production of glucagon which is a hormone responsible for increasing glucose levels in the body

While menopause itself isn't a separate indication, the medication works on underlying metabolic mechanismsappetite dysregulation and insulin resistancethat menopause triggers