This is when our body makes much of it and it hurts our melanocytes
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doi: 10.23937/2474-3658/1510187 207 OlagnierD.FarahaniE.ThyrstedJ.Blay-CadanetJ.HerengtA.IdornM.et al
observed that esaxerenone, a nonsteroidal selective compound, effectively decreased the expression of MCP-1 and inhibited the infiltration of inflammatory cells in DKD by suppressing ROS levels (212)
KD reduces inflammatory cytokines, such as IL-6, IL-17, and IL-23, which have a significant role in the etiopathogenesis of psoriasis (201, 205)
Superoxide anion radical (O 2 ) is the primary cell-generated ROS which triggers a cascade of reactions and, therefore, the formation of secondary ROS, either directly or via enzymatic and metal-catalyzed processes, counting on the cell compartment