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Cellular uptake studies revealed a 5.3-fold increase in drug internalization in Caco-2 cells when encapsulated in nanoparticles

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Further research will be required to determine if SYGL-1 and LST-1 are required to selectively target different FBF mRNA targets, or if they assist in regulating similar targets as is suggested based on the increase in GLD-1 levels in both lst-1 and sygl-1 mutants (Brenner and Schedl, 2016)

In contrast, excessive caffeine intake can worsen headaches