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The differential expression of circular RNAs (circRNAs) and microRNAs (miRNAs) in cancer is a useful predictor of their potential role in cancer progression, whether as oncogenes or tumour suppressors [69]

Supporting this, data from our functional enrichment analysis of the transcriptome revealed notable upregulation of oxidative phosphorylation and the oxidative damage response in hepsin / mice treated with saline (data not shown)