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Since B vitamins are water-soluble and must be replenished daily, taking one B vitamin in very high amounts for a long period may affect the balance of the others

Some B complexes found over the counter contain very very little thiamine, as little as 12.5mg/kg, so these would be such a massive volume they should be avoided unless there's no other option

This is Foods rich in vitamin B12 fish and seafood meat eggs dairy products fortified plant-based dairy alternatives fortified breakfast cereals fortified nutritional yeast Vitamin supplements can make up for a shortfall in the diet, especially for vegans and strict vegetarians

Some people notice mild side effects like redness, slight soreness, or light-headedness, but these usually fade quickly

Vitamin B12, folate, and the methionine remethylation cyclebiochemistry, pathways, and regulation