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Overgaard RV, Hertz CL, Ingwersen SH, Navarria A, Drucker DJ (2021) Levels of circulating semaglutide determine reductions in HbA 1c and body weight in people with type 2 diabetes

Use proper needle technique by pinching the skin, inserting the needle at a 90 angle (or 45 if your skin is very thin), and choosing smaller-gauge needles for less discomfort

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It is approved as an adjunct to a reduced-calorie diet and increased physical activity in people with obesity or overweight and at least one weight-related comorbidity, including dysglycaemia (prediabetes or T2D), hypertension, dyslipidaemia, OSAS or CVD