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The established Observed Safe Level (OSL) for chronic, long-term supplementation is generally recognized as 2,000 mg per day, though higher doses have been used safely in monitored trials

Ecotoxicology 5:217225 Van Ravenzwaay B, Coelho-Palermo Cunha G, Leibold E, Looser R, Mellert W, Prokoudine A, Walk T, Wiermer J (2007) The use of metabolomics for the discovery of new biomarkers of effect

1 Latin American countries have a clinical or subclinical deficiency rate of approximately 40%

An examination of myricitrins anxiolytic properties was carried out using the elevated plus maze (EPM) in mice, showing that myricitrin effectively increased animal time on the EPM, an anxiolytic effect, without causing sedation or the myorelaxation seen with diazepam (Pereira et al., 2011)

Results vary and depend on lifestyle, nutrition and consistency

System Clearance: Within 24 hours, a significant portion of the administered dose will likely be metabolized