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Effect of once-weekly exenatide in patients with type 2 diabetes mellitus with and without heart failure and heart failurerelated outcomes: Insights from the EXSCEL trial
GLP-1 works in the body by: Stimulating insulin release from your pancreas to lower blood sugar Blocking secretion of glucagon, a hormone that raises blood sugar Delaying stomach emptying to control blood sugar and prolong feelings of fullness Decreasing appetite and improving satiety, leading to eating less Lets dig into the ways that what you eat, how you eat and other lifestyle factors can influence the stimulation of GLP-1 in your body
Perhaps the best single paper on this topic comes from Oprea and colleagues and was published in the British Journal of Anaesthesia in July 2025
Use an insulated bag with ice packs for trips longer than a few hours
Even at microdoses, these effects can contribute to better heart health, especially for individuals with risk factors like high cholesterol or hypertension
