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Renue is confident enough in these tablets' ability to bypass hepatic metabolism that it's willing to underdose them significantly, but how that translates to NMN in the bloodstream, and eventually intracellular NAD+, is unclear, creating question marks for both safety and efficacy

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Therefore, we immunostained liver tissue sections with the common leukocyte antigen, CD45, and with FSP1, a marker of a specific subpopulation of inflammatory macrophages (Fig

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