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Registered Phase I study A safety and pharmacokinetics study was registered, but public results sufficient to establish a safety profile have not been posted

However, when different proportions of ethanol (5%, 10% and 20%, v/v) were added in our preliminary formulations, all test solutions precipitated, likely due to the poor solubility of high-dose DOX in ethanol and the resulting instability of the whole solution system (11)

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