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(35) reported that enzymatic activity were poor predictors of clinical manifestations and that they could be more related to genotype instead

CAFs can also promote cancer growth and invasiveness, and both CAFS and ROS are linked through the increases in ROS-generated CAFs to which most cancers respond by increasing the expression of antioxidant genes 52,53,54 (Fig

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Trained immunity: A program of innate immune memory in health and disease