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Key Context Under the 2022 Inflation Reduction Act (IRA), which authorized the negotiations, drugmakers must offer covered entities the lower of the MFP or the 340B ceiling price, but not both

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Studies have also demonstrated the role of IGF-I in promoting mitosis of cells, and its ability to particularly promote the uterine smooth muscle cells proliferation, therefore making it a potential contributor to the formation of UF (Maruo et al., 2007

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While stopping short of a recall, Janssen withdrew the drug amid mounting concerns and the wide availability of alternative treatment options