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In clinical trials, participants taking semaglutide lost an average of 15% of their body weight, compared to only 2.6% for those on a placebo

306 For example, the reduction in TNF-, IL-1, and IL-6 helps regulate local and systemic inflammatory responses

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The efficacy of hypoglossal nerve stimulation as a therapy for OSA is influenced by various factors, including age, BMI, pattern of upper airway collapse, and certain endotypic OSA factors, including arousal threshold and upper airway muscle compensation [49]

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