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Research now suggests obesity may create long-lasting changes in: Hormones Brain reward pathways Inflammation Immune function Appetite regulation This helps explain why maintaining weight loss can be difficult even after successful treatment

doi:10.1016/j.cgh.2021.03.045

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Molecular Microbiology, 68 (1), 416

Neurological diseases can disrupt iron absorption and transport, leading to excessive iron accumulation, increased oxidative stress, and resulting in cellular ferroptosis

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