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s -Cysteinylation of SOD1 prevents the inhibitory action of hydrogen peroxide on SOD1, 207,208 which contributes to an increased antioxidant potential of cancer cells and thereby protects them from oxidative damage

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This inhibition is achieved by capsaicins interaction with the PPAR-poldip2-Nox4 pathway [225]

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Supporting ingredients for NAD+ production While many companies sell NAD+ boosters on their own, others see fit to pair NMN or NR with additional components