What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data
There is, however, no shortage of worthy scientific advances from which the Nobel Prize committees can pick
In studies of people with type 2 diabetes, Mounjaro was better than Ozempic at lowering HbA1C, with reductions of around 2.3% and supporting weight loss, with participants shedding 15.3% of body weight, depending on the dose
These drugs are also being studied to potentially treat alcohol and substance use disorders
Patients with a pancreatitis history or severe gastrointestinal disease should explore different alternatives with their healthcare provider
If youre like most patients who need tirzepatide or semaglutide, your body is fighting weight loss on multiple hormonal fronts