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LunyeraJKirengaBStaniferJWKasoziSvan der MolenTKatagiraWet al

For the mediation analysis on the histology endpoints evaluating change in body weight as mediator, data were based on complete-case on-treatment measurements to evaluate the mechanistic action of semaglutide in MASH (hence, data outside the on-treatment observation period were excluded)

In trials, weight change is measured across weeks and months, not as a same-day effect

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