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74 Through GLP1R activation and its crosstalk with insulin and IGF1 pathways, incretin mimetics restore mitochondrial integrity, attenuate neuroinflammatory cascades, and preserve synaptic resilience
Semaglutide is a GLP-1 receptor agonist that: Regulates appetite by mimicking a natural gut hormone Slows digestion and increases feelings of fullness Improves insulin sensitivity and lowers blood sugar Originally FDA-approved for type 2 diabetes (as Ozempic ), semaglutide is now approved for weight loss under the brand name Wegovy for people with obesity or overweight with weight-related conditions
doi: 10.4158/EP14284.CR 17 AcharyaRKabadiUM
Patients begin at a lower dose and gradually increase over several months to reach the full maintenance dose
Unopened pens can last up until the labeled expiration date, as long as theyre stored properly