In the process of purine synthesis, 5-phosphoribosyl--pyrophosphate (PRPP) generated from the pentose phosphate pathway (PPP) is converted to phosphoribosyl--amine (PRA) through the action of phosphoribosyl pyrophosphate amidotransferase (PPAT) when an amide group from glutamine is introduced
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He K, Hu H, Ye S, Wang H, Cui R, Yi L
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PMID: 28 TripolinoCCiaffiJPucinoVRuscittiPvan LeeuwenNBorghiCet al