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Clinical trial data suggest that gastrointestinal adverse effects typically peak during dose escalation and diminish with continued therapy at stable doses

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Plutzkys team did emphasize that this study was built to study high-risk heart patientsthey were not evaluating the drugs impact when it comes to reducing the risk of first-time cardiovascular events in patients with no previous heart issues.

The 0.5 mg phase is also when dizziness and headaches tend to appear

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Among those who had used the drugs for diabetes, the pattern was more favorable: 56 percent kept losing or stayed the same, while 44 percent gained