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FOXO4-DRI has a rapidly expanding and high-impact published research base, with studies published across Nature, Nature Communications, Communications Biology, Aging, Frontiers in Bioengineering and Biotechnology, and PMC since its foundational description in 2017

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These numbers appear to put CT-388, which Roche acquired in its $2.7 billion Carmot buy, in line with Eli Lillys Zepbound, according to William Blair analysts

277 The reported variation in the weight loss for the different GLP-1 analogues currently used to treat T2D is possibly related to their ability to penetrate the CNS, allowing for central GLP-1R binding

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