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This means it takes a minimum of 16 to 20 weeks just to reach the full therapeutic dose

The same was seen when analyzing normalized collagen content in individual cardiac regions separately (Figure S7)

10.1111/jvim.13817

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These early studies confirmed the once-weekly dosing feasibility and identified the gastrointestinal side effectsprimarily nausea, vomiting, and diarrheathat would become characteristic of GLP-1 receptor agonist therapy