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MSNA values, although increased in both central and peripheral obesity, are greater in individuals with an abdominal or central distribution of body fat (Grassi et al., 2004), particularly with visceral obesity (Alvarez et al., 1995), central chemoreflex hypersensitivity (Narkiewicz et al., 1999a) and blunted muscle metaboreflex (Negrao et al., 2001)
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Future decision-making frameworks based on phenotype stratification and Bayesian integration should prioritize identifying who requires long-term maintenance versus a short-term window, and how to minimize the reproductive costs of post-discontinuation rebound
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Generation of reactive oxygen species, lipid peroxidation, and human sperm function
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