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Much of the reported 40% lean mass loss with GLP-1 use is coming from the liver," explained exercise physiologist Keith Baar, a professor of Neurobiology, Physiology and Behavior and Physiology and Membrane Biology

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Comparison to Other GLP-1 Medications Retatrutide's BP reduction exceeds other obesity medications: Semaglutide (Wegovy): -6.2 mmHg systolic Tirzepatide (Zepbound): -8.0 mmHg systolic (15mg, SURMOUNT-1) Retatrutide: -14.0 mmHg systolic The addition of glucagon receptor agonism likely contributes

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