Lewy AJ, Bauer VK, Hasler BP, Kendall AR, Pires ML, Sack RL
These may include lack of sleep, smoking, food intolerances, diets high in sugars and processed foods, excess alcohol intake, and hormone or immune imbalances
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a) Insulin only b) GLP1 and GIP c) Glucagon only d) Amylin & somatostatin Answer: b) GLP1 and GIP The glucose-lowering effect is: a) Constant b) Glucose-dependent c) Hypoglycemia-prone d) Insulin-independent Answer: b) Glucose-dependent Sitagliptin is primarily excreted via: a) Feces b) Urine c) Bile d) Sweat Answer: b) Urine A rare but serious side effect is: a) Hypoglycemia b) Pancreatitis c) Hypothyroidism d) Bladder cancer Answer: b) Pancreatitis Protein binding is approximately: a) 10% b) 38% c) 80% d) 99% Answer: b) 38% DPP4 inhibitors differ from GLP1 agonists by: a) Oral vs injection b) Cost only c) Efficacy only d) Indication only Answer: a) Oral vs injection Combination with sulfonylureas increases risk of: a) Pancreatitis b) Heart failure c) Hypoglycemia d) Weight gain Answer: c) Hypoglycemia Dose scheduling is: a) Multiple times daily b) Once daily c) Every other day d) Weekly Answer: b) Once daily Sitagliptin therapy is least likely to cause: a) Hypoglycemia b) Weight gain c) Nasopharyngitis d) Pancreatitis Answer: a) Hypoglycemia Onset of action occurs within: a) Minutes b) Hours c) Days d) Weeks Answer: b) Hours Compared to saxagliptin, sitagliptin has: a) Higher potency b) Lower potency c) Similar profile d) Different mechanism Answer: c) Similar profile Sitagliptin should be dose-adjusted for: a) Liver disease b) Renal impairment c) Hypothyroidism d) Pregnancy Answer: b) Renal impairment Weight effect of sitagliptin is: a) Weight gain b) Weight loss c) Weight neutral d) Unknown Answer: c) Weight neutral Sitagliptin carries risk of heart failure
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Some introduce the medication gently, while others deepen appetite suppression and stabilise weight loss patterns
