Delivery of therapeutics across the BBB The unique properties of the BBB maintain brain homeostasis, but at the same time pose an obstacle for the delivery of therapeutic molecules and cells
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"The effects of human growth hormone and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice." Endocrinology Publication confirming the effectiveness in body weight reduction and the mechanism of action
We believe that this same level of precision should be applied in your lab
In contrast, the 2,3-diamino substitution in the 1MQ scaffold (2,3-diamino-1MQ) displayed high passive permeability (Table 1), but moderate bi-directional active transport with moderate efflux ratio (Table 2)
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