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Studies have found that semaglutide leads to significant weight loss: after 68 weeks, half of the participants lost 15% of their body weight, and nearly a third lost 20%

[Google Scholar] 107.Umpierrez GE, Smiley D, Zisman A, et al

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Experts say a healthy frequency can range anywhere from three times a day to three times a week

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This gap exists because real-world adherence is imperfect, escalation timing is variable, and lifestyle factors are uncontrolled