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Research Growth-hormone secretagogue pharmacology Ghrelin / GHS-R1a receptor signalling in vitro Regulation of pulsatile GH release in animal models GH/IGF-1 axis and body-composition studies in rodents Bone-metabolism research models Comparative studies across growth-hormone releasing peptides Analytical reference use for HPLC/MS method development Advantages In preclinical rodent models, used to investigate stimulated release of growth hormone from pituitary somatotrophs

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Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, et al

Kurniawan, H

Many acute studies utilize a completely different exposure pattern with very high CS concentrations, which is not necessarily comparable to the smoking regimen used for chronic studies [22, 23]

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