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It can also cause relaxation, euphoria, and a decrease in inhibitions

Beyond simple biomechanics, where each 1 kg of weight gain multiplies knee joint load by 34 kg, accelerating cartilage wear and activating pathogenic pathways like Wnt/ -catenin, the endocrine function of fat is paramount (14, 15)

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Meng L, Zhang Q, Yang J et al (2020) Ptrcdpk10 of Poncirus trifoliata functions in dehydration and drought tolerance by reducing ROS accumulation via phosphorylating PtrAPX

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