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Too little sleep can cause your blood vessels to leak and subsequently mix with those fluids, leading to dark circles

Glutathione interferes with the enzyme tyrosinase, which is essential for melanin production

Multiple endocrine neoplasia syndrome type 2 carries similar restrictions

The key takeaway is that significant side effects are not common, but it's always best to be aware of what you might experience as your body adjusts

doi: 10.1006/abbi.1997.0470 225 BerendjiDKolb-BachofenVMeyerKLGrapenthinOWeberHWahnVet al

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