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At the chemical level the oxido-reductive (redox) status of a biological system can be quantitatively expressed through the relative levels of some biological indicators such as soluble thiols, nucleotide cofactors and other molecules which coexist in the organism as the pair of their reduced and oxidized form

Van Dycke, K

& Gavrilova-Jordan, L

They mainly come from the cartilage, bones, and skin of cows, fish, or chickens, and have high bioavailability

There are many adverse effects, ranging from serious ones like hepatotoxicity to minor ones like peripheral neuropathy, joint, pain, visual impairment, nausea, and vomiting (El-Sadr et al., 2001

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