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Mitochondrial morphology imaging Mitochondrial morphology was observed under the confocal microscopy following staining with the mitochondria targeting dye MitoTracker Red CMXRos (Beyotime Biotech)

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Discussion Previous studies have shown that long-lasting bladder tissue remodelling occurs in response to UPEC infection, and this remodelling is accompanied by changes in susceptibility to subsequent infection, depending on previous infection outcomes 5,6,7