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Khomich et al., 2018

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Taken together, human in vitro and in vivo studies suggest that CYP3A4 plays a minor role in the bioactivation of low dose APAP

used high-glucose treatment in SH-SY5Y cells to mimic diabetic neuropathy and explored the effect of the GLP-1R agonist exendin-4 on diabetic neuropathy ( 3.2 In vivo evidence Liu et al

Robust evidence from landmark CVOTs, such as LEADER, SUSTAIN-6, and SELECT has proven GLP-1 agonists serve as essential treatment options for T2DM patients at high cardiovascular risk and indicate their growing applications in HFpEF and non-diabetic patients and cerebrovascular disease