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Taking a closer look at the cholesterol concentration ( Supplementary Table 5 ), it maintained the initial level until 72 h pi , before reaching a significantly lower level from d 7 pi until the end of the study

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Furthermore, metformin combined with 1.8 Gy radiation significantly increased the proportion of SW837 cells in late apoptosis, when compared to unirradiated metformin treated cells ( Figure 3D )

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Conclusion To sum up, **ovarian cysts** are often the main cause of **irregular periods** that occur mostly because of hormonal imbalances or interrupted ovulation

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