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The upregulation of IGFBP4 (encodes for a protein that binds insulin-like growth factors I and II 26 ), was shown to function as a potent tumor suppressor in hepatocellular carcinoma and delay tumor formation in prostate cancer cells 41,42

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Cancer chemoprevention by tea polyphenols through mitotic signal transduction blockade

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5.1 Responses to abiotic stress Abiotic stress refers to non-biological environmental factorsincluding drought, extreme temperatures, soil salinity, flooding, soil acidity (low pH), nutritional deficiencies, heavy metal toxicity, and ultraviolet radiationthat limit plant growth, survival, or reproduction (Lull et al., 2008

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1996 juil.;17(5):320-4

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Adult reference intake (8400 kJ / 2000 kcal)

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