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Their mean age and body mass index were 36.5 years and 28 kg/m 2 , respectively

If atorvastatin would bind and activate RyR2, the main isoform expressed in cardiac tissue, this could lead to dangerous arrhythmias similar to catecholaminergic polymorphic ventricular tachycardia (CPVT), frequently linked to gain-of-function mutations in RyR2 9,30

For example, these cells detect carbohydrates and release GLP-1 to help manage blood sugar, or detect fat and release CCK to signal fat metabolism

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"Wegovy (Novo Nordisk Pharmaceuticals Pty Ltd)"

Depending on the isotope, different reaction setups were employed (HFP-1, HFP-2, or HFP-3) on a 4.425 mol scale, at reaction times of 4860 h, at RT or 40 C