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The FDA has flagged concerns about thyroid tumors, including medullary thyroid carcinoma (MTC), based on animal studies, though the risk to humans isnt fully understood

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Conflict of interest CR has received personal fees from Boehringer Ingelheim, GI Dynamics, Herbalife, Johnson and Johnson, Keyron, Eli Lilly, and Novo Nordisk outside the submitted work

The 0.25mg starting dose becomes 10 units instead of 5

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Recurrence after recovery is rare