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10.1007/s10555-024-10192-9 [DOI] [PMC free article] [PubMed] [Google Scholar] 9.Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares M, de Souza GA, Fidalgo TM, Araujo AC, de Souza Gonzaga HF, de Bortoli Teixeira D, de Silva Ullmann O, Sloan T, Sloan KP LA (2022) GLP-1a: going beyond traditional use
In both peptides, the N-terminal histidine sits in an enclosed pocket-forming hydrophobic and hydrogen bond interactions with E364 6.53 , E387 7.42 , R310 5.40 , Y241 3.44 , W306 5.36 , I313 5.43 and Q234 3.37 however, these interactions are more persistent with GLP-1, and this is likely linked to the stability of interactions of Glu9 and with residues at the base of the binding cavity (Supplementary Table 3, Supplementary Movie 1)
Are there side effects to different copper peptide types