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The One-Line Rule Refrigerate at 36 to 46F
In reviewing the content of the claims in this batch of warning letters, most of the concerning language on online websites advertising these products that was flagged by the FDA is unsurprising, including: Named the brand product as a comparative reference or therapeutic equivalent Stated the compounded product was a generic of the brand product Included efficacy claims for the compounded product Used the words FDA-approved in the advertising copy But some of the language that was flagged by the FDA was less direct, with the FDAs expressed concern being that the advertising may have given the impression of FDA approval
A 2024 Trustpilot transparency report noted that platforms with active response engagement on long-form reviews tend to score better on average
Gallstones and alcohol abuse stand out as the primary triggers for AP, while genetic factors, medications, and smoking also play contributing roles (Wolfe et al., 2020)
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