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Holthoff et al., 2005

In another study that evaluated the effect of 6 g/m 2 (i.e., dosage based on body surface area) twice daily glutamine versus placebo (three weeks followed by three weeks washout) in 49 children and adolescents receiving vincristine for various cancers, glutamine-treated patients reported significantly greater improvements in sensory function and quality of life compared with placebo-treated patients (Sands 2017)

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However, as the results could not be reproduced by other groups [164], it was finally realized that the authors of the original study dissolved APAP in DMSO instead of saline

Some individuals may experience adverse reactions, including increased joint laxity and gastrointestinal issues

We constructed the skin organoids by extracting the skin cells from newborn mice and added XN to the skin organoids