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Retest before escalating methyl donors SAMe or methionine may be appropriate for selected low-SAM patterns, but adding more methyl donors may not overcome persistent SAH inhibition

Shapiro MR, Wasserfall CH, McGrail SM et al (2020) Insulin-like growth factor dysregulation both preceding and following type 1 diabetes diagnosis

otherwise, data distribution was assumed to be normal but this was not formally tested

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